DR.MELAXIN
Dr.Melaxin TX Ampoule RX Dark Spot Correcting Serum 30ml
Dr.Melaxin TX Ampoule RX Dark Spot Correcting Serum 30ml
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THE PROBLEM WITH STANDARD DARK SPOT SERUMS
You've been treating the symptom. This targets the source.
Most brightening serums dilute their actives to the point of ineffectiveness, or rely on single-pathway inhibitors that plateau after weeks. Freckles, melasma, post-acne marks — these require a high-concentration, multi-target approach that works at the biochemical level where pigmentation is actually produced.
DR.MELAXIN
TX Ampoule RX Dark Spot Serum
"Pharmaceutical-concentration TX in a serum format — richer than serum, targeted at the root of pigmentation."
The TX Ampoule RX delivers Tranexamic Acid at 43,000 ppm — a concentration uncommon in retail skincare — combined with 43,000 ppm Niacinamide, Glutathione, Adenosine, and Asiaticoside. Where the TX Serum Cleanser acts at cleansing stage, this ampoule acts deep in the skin through continuous leave-on contact. The result: an accelerated dark spot correction programme for Korean skincare users who demand clinical-level actives.
Our Licensed Korean Pharmacist & Certified Cosmetic Formulation Manager identified this formulation as one of the highest TX-concentration leave-on treatments available in K-beauty retail. The concentration is intentional — not a labelling tactic but a pharmacologically meaningful dose.
What Happens First
Within 10 Minutes
Serum absorbs completely without tackiness. Skin feels hydrated and smoother at the surface.
Next Morning
Dark marks appear slightly less saturated. Skin tone reads more unified in natural light.
The Concentration Question
"Is 43,000 ppm really necessary, or is it just a number on the label?"
Tranexamic Acid's efficacy is dose-dependent. At 2–3% (20,000–30,000 ppm), published studies show measurable melanin reduction. At 43,000 ppm (4.3%), this formula exceeds the published threshold by a meaningful margin. Combined with Niacinamide at the same concentration to inhibit melanosome transfer, the formula is built to work on multiple pigmentation pathways simultaneously.
As our pharmacy-credentialed formulation reviewer explains: the TX + Niacinamide dual-concentration approach in this ampoule is among the most precisely calibrated in the Korean skincare market — not a single active padded with marketing copy, but a dual-primary formulation.
What to Expect, Week by Week
Days 1–3
Skin hydration improves noticeably. Surface texture feels smoother and serum absorbs readily into skin.
Week 1
Edges of dark spots appear less defined. Existing marks begin to look lighter at their centre.
Week 2
Overall skin tone appears more even. Post-inflammatory hyperpigmentation (PIH) marks showing visible reduction.
Week 4
Dark spots, freckles, and melasma patches measurably reduced with consistent once or twice-daily use. Individual results may vary.
Key Actives — What They Do
Tranexamic Acid
INCI: Tranexamic Acid · 43,000 ppm (4.3%)
Inhibits plasminogen activation, blocking the UV-triggered arachidonic acid cascade that stimulates melanocyte activity. High-dose leave-on delivery maximises cumulative effect.
Niacinamide
INCI: Niacinamide · 43,000 ppm (4.3%)
Blocks melanosome transfer from melanocytes to keratinocytes. Independently reduces skin yellowing and regulates sebum at the same dose.
Glutathione
INCI: Glutathione
Switches melanin synthesis from dark eumelanin to lighter pheomelanin. Provides antioxidant protection against oxidative stress that triggers pigmentation.
Adenosine + Asiaticoside
INCI: Adenosine / Asiaticoside
Adenosine supports skin elasticity and reduces the appearance of fine lines. Asiaticoside (Centella asiatica) soothes post-treatment sensitivity and supports barrier recovery.
Skin Type Compatibility
Hyperpigmentation
Primary use. TX + Niacinamide dual high-dose targets multiple melanin pathways simultaneously.
Melasma / Freckles
43,000 ppm TX exceeds the published effective threshold for melasma reduction.
Post-Acne Marks
Reduces PIH effectively through melanosome transfer inhibition and barrier soothing.
Oily / Combination
Niacinamide regulates sebum. Lightweight serum texture absorbs without pore-clogging.
Sensitive Skin
TX and Niacinamide are well-tolerated actives. Patch test recommended for reactive skin.
Professional / Esthetic
Pharmaceutical-grade concentration used in professional brightening programmes.
One Unexpected Use Case
Esthetic professionals in Korea often apply this ampoule under an occlusive sheet mask for an intensified 15-minute pigmentation protocol. The occlusion increases penetration without altering the active chemistry — a simple professional trick that amplifies retail-grade results significantly.
Korean skincare knows: the active makes the difference. 43,000 ppm makes the argument.
Why Our Pharmacist Chose This
Licensed Korean Pharmacist & Certified Cosmetic Formulation Manager — The dual 43,000 ppm concentration of Tranexamic Acid and Niacinamide is pharmacologically significant. TX operates pre-melanin (blocking the trigger), while Niacinamide operates post-melanin (blocking the transfer). Having both at effective doses in a single leave-on serum is the standard I expect from a serious pigmentation product, and this one meets it. That is why it is listed on cosmogangnam.com.
Every product on cosmogangnam.com passes our pharmacist's ingredient review before listing.
What Customers Notice
"After 3 weeks my freckle marks are noticeably faded. I use it every night under my moisturiser and the difference is clear in photos."
— Verified Customer · Hyperpigmentation / Combination skin
"Lightweight but extremely effective. My post-acne marks are the lightest they've been in years. This is my permanent routine now."
— Verified Customer · Oily / Acne-prone skin
"I was sceptical about the concentration claim but after one month my skin tone is genuinely more even. Ships fast from South Korea too."
— Verified Customer · Dry / Sensitive skin
Individual results may vary.
Frequently Asked Questions
What does the TX Ampoule RX Dark Spot Serum do?
It delivers high-concentration Tranexamic Acid (43,000 ppm) and Niacinamide (43,000 ppm) in a leave-on serum format to inhibit melanin production and block its transfer to the skin surface. Target concerns include freckles, melasma, dark spots, and post-inflammatory hyperpigmentation.
Who should use it?
Anyone targeting pigmentation, dark spots, freckles, or uneven skin tone. Especially effective for oily and combination skin where Niacinamide provides dual brightening and sebum-regulation benefits. Esthetic professionals use it in in-clinic brightening protocols.
How do I use it in my routine?
Apply 2–3 drops to clean, toned skin morning and/or evening. Pat gently — do not rub. Allow to absorb before applying moisturiser. For enhanced results, apply before a sheet mask and leave for 15 minutes. Follow with SPF in the morning. Patch test before first full-face use.
Is it safe for sensitive skin?
Tranexamic Acid and Niacinamide are considered low-irritation actives with published tolerability data. Asiaticoside provides additional calming support. That said, at 43,000 ppm, we recommend starting with once-daily use and performing a 24-hour patch test before full application.
What makes it different from other brightening serums?
Most brightening serums use 2–5% Niacinamide with trace amounts of brightening actives. This formula leads with two actives both at 4.3% — TX and Niacinamide — operating on different points in the pigmentation cascade. Our pharmacy-credentialed reviewer specifically selected it for this dual-primary architecture.
How long until results?
Texture improvement and initial tone-evening from Week 1. Visible dark spot reduction typically from Week 2. Significant melasma and freckle reduction generally by Week 4 with consistent use. Individual results may vary depending on skin condition and sun exposure habits.
How to Use
- When: Morning and/or evening, after toner and before moisturiser.
- How much: 2–3 drops per application.
- Application: Apply to clean, toned skin. Pat gently to absorb — do not rub or pull.
- Layering: Follow with moisturiser. In the morning, always apply SPF after moisturiser to protect brightened skin. Pairs with TX Serum Cleanser and TX Cream for full TX brightening routine.
- Patch test: Apply to inside wrist for 24 hours before full facial use. Discontinue if irritation occurs.
Product Details
| Brand | DR.MELAXIN |
| Volume | 30 ml |
| Texture | Lightweight serum / ampoule |
| Key Actives | Tranexamic Acid 43,000ppm, Niacinamide 43,000ppm, Glutathione, Adenosine, Asiaticoside |
| Skin Type | All skin types; especially hyperpigmentation, oily, combination |
| Origin | Made in South Korea |
| Regulatory | MFDS Compliant |
Full Ingredient List (INCI)
Water, Butylene Glycol, Glycerin, Tranexamic Acid (TX — melanin production inhibitor; 43,000 ppm), Niacinamide (melanosome transfer inhibitor; 43,000 ppm), Glutathione (antioxidant brightener), Sodium Hyaluronate, Panthenol, Allantoin, Adenosine (elasticity support), Asiaticoside (Centella asiatica — barrier soother), Dipotassium Glycyrrhizate, 1,2-Hexanediol, Carbomer, Triethanolamine, Disodium EDTA, Ethylhexylglycerin
Ingredients may vary slightly by batch. Always refer to the physical product label.
Free Shipping
On orders over $80
Ships to 57 Countries
Ships from South Korea
US Duties Covered
No surprise charges at delivery
This product is a cosmetic and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. All claims refer to cosmetic appearance only. Results are not guaranteed and individual results may vary. Always perform a patch test before first use.
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